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Discovered in the 1970s during a study on sleep patterns, DSIP has been extensively researched for its potential benefits in enhancing sleep quality, reducing stress, and modulating endocrine regulation

however, variations in concentration ranges, exposure times, delivery methods, and oxidative stress inducers influence effect sizes and statistical power

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Therefore, the putative pathomechanisms associating both copper excess and deficiency with MASLD development and progression are reviewed

Specifically, the study reveals a significant reduction in serum melatonin levels in the model group compared to the control, suggesting the induction of stress